Soil salinization is a global problem which restricts the choice of crops for cultivation. Management and reclamation of saline soils using costly and time consuming methods such as installation of drainage systems is beyond the reach of poor farmers. Therefore, it is important to look for alternate crops which are more salt-tolerant. One such crop is quinoa (Chenopodium quinoa W.), which has high nutritious value and capacity to grow in marginal conditions. As crops vary in their tolerance to salinity, they need to be evaluated for different salinity conditions. This study was conducted to evaluate 5 quinoa genotypes (ICBA-Q1, ICBA-Q2), ICBA-Q3, ICBA-Q4 and ICBA-Q5) for their salinity tolerance under four artificially induced salinity (5, 10, 15, 20 dSm-1) levels. The parameters studied were rate of seed germination, plant height, dry biomass, nutritional content and grain yield. The results indicate that salinity had an inhibitory effect on all parameters. Out of 5 quinoa genotypes, ICBA-Q3 and ICBA-Q4 proved more salt-tolerant under saline conditions with regard to dry biomass and grain yield and nutritional contents. Therefore these two genotypes are recommended to farmers for large-scale adaptation in the salt-affected areas of Ethiopia.